Birmingham's Craig Gardner is in contention to start after making his comeback from injury as a substitute in the midweek win over Aston Villa.
The Blues are hopeful Alexander Hleb will overcome a calf strain.
Tottenham's Michael Dawson makes his long-awaited return to the squad after the ankle problem he picked up playing for England in early September.
Injury has ruled Rafael van der Vaart out for three weeks, and Younes Kaboul for a fortnight.
The explosive end to Wednesday night's Carling Cup quarter-final victory over Aston Villa tarnished what was a famous derby win for Birmingham City. The FA are bound to come down hard on the Blues following the pitch invasion that led to ugly skirmishes with Villa fans and the police.
Manager Alex McLeish has been keen to direct attention away from the behaviour of the troublemakers and onto the achievements of his players. While there is nothing sweeter than a triumph over the Villa, he will have swiftly refocused his players on to the club's number one goal at the start of the season - Premier League survival.
Yet again, Tottenham are beset by an injury crisis and manager Harry Redknapp is down to the bare bones. Although these days at White Hart Lane, even the players regarded as the bare bones of his squad are experienced internationals.
Tottenham have 25 full internationals in their ranks, a total matched only by Manchester United, which is a real sign of their increasing threat to the top-flight's elite.
This has also been helped in recent weeks by their growing reputation as the league's comeback kings, and they picked up another three points with a late goal last week against Liverpool. Given that there has been a 90th-minute goal in five of the last six Premier League games between these sides, any fan would be advised not to leave St Andrew's early.
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