Liverpool have the option of reverting to a more attack-minded line-up for this rearranged Premier League game.
New signing Maxi Rodriguez could make his full debut, while Albert Riera and Alberto Aquilani may be promoted from the bench.
Tottenham manager Harry Redknapp says he will rotate his side, with Peter Crouch among those expected to benefit.
Spurs are hopeful that Ledley King will be fit to play, having missed Saturday's home draw against Hill.
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Liverpool
Suspended: None Doubtful: None
Injured: Benayoun (broken rib), El Zhar & Kelly (both ankle), Gerrard (hamstring), Johnson & Torres (both knee)
Tottenham
Suspended: None Doubtful: King (knee)
Injured: Assou-Ekotto, Hutton, Lennon & Woodgate (all groin), Cudicini (broken wrists)
MATCH PREVIEW
Liverpool may have laboured while Tottenham have been lauded, but a home win at Anfield would leave just a point between them in the pursuit of a Champions League spot.
It is shaping up to be a four-way battle for fourth place, with Liverpool reprieved at the weekend by the failure of the other contenders to even manage a goal between them. Liverpool's prospects will be given renewed hope if they can win this rearranged fixture, which fell victim to the freezing temperatures earlier this month.
Tottenham were unlucky to find Hull goalkeeper Boaz Myhill in inspired form in Saturday's goalless draw and their progress has been so impressive that their manager Harry Redknapp, a renowned wheeler-dealer, claims there is not one player he is thinking of signing during the January transfer window.
Nonetheless, Redknapp has been unable to buy a win at Anfield; his previous 500 Premier League games as a manager do not include a single away victory against Liverpool. He has only managed four draws in 12 visits, with his side failing to score on nine occasions.
Redknapp will be acutely aware this is an opportune time to end Liverpool's stranglehold, both on this fixture and a top-four finish.