Tottenham striker Jermain Defoe will begin a three-match ban for his sending off against Aston Villa.
Defoe's absence means Spurs will recall Roman Pavlyuchenko or Peter Crouch, while Luka Modric should play despite suffering cramp at Villa.
Newcastle will be without captain Kevin Nolan, who picked up his fifth booking of the season against Manchester City.
Manager Alan Pardew has said that goalkeeper Tim Krul will retain his place despite his error on Boxing Day.
Having won their two previous Premier League games in the capital this season, Newcastle will hope to claim a hat-trick of London scalps against Tottenham, who have lost six of their last seven top-flight matches against the Magpies.
Toon target man Andy Carroll was the match-winner when Newcastle won at Ars*nal and West Ham earlier this term. The 21-year-old already has 11 league goals this season, reportedly catching the eye of Spurs boss Harry Redknapp.
However, there appears to be little chance of Newcastle letting Carroll go on the cheap during the January transfer window, with manager Alan Pardew insisting his side have to demonstrate a "big club mentality" and hold on to their prize asset. He will therefore be encouraged that centre-back Steven Taylor, who looked set to leave St James' Park for nothing next summer, has agreed a new contract.
Pardew, who replaced former Spurs stalwart Chris Hughton at Newcastle, has a mixed record against Tottenham. He was in charge of West Ham when they beat Spurs on the final day of the 2005/06 season, denying Martin Jol's team a Champions League spot. However, his Charlton side were relegated from the Premier League in 2007 following a 2-0 defeat to Tottenham.
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