Tottenham are likely to be without Rafael van der Vaart due to a calf injury, but fellow playmaker Luka Modric could return in his place. Goalkeeper Heurelho Gomes is still not fit and Jermain Defoe and Michael Dawson remain long-term absentees.
Wolves centre-back Christophe Berra is missing through suspension and will be replaced by Richard Stearman.
Steven Mouyokolo is finally fit after thigh and ankle injuries, and Ronald Zubar is back after hamstring trouble.
Spurs come into this match off the back of their impressive Champions League draw away at Werder Bremen, which showed they are finding their feet in Europe's premier cup competition.
But manager Harry Redknapp will not tolerate a repeat of what happened last month. The thrill of reaching the group stages with a midweek win over Young Boys left Spurs with a stinging Champions League hangover as they then suffered a shock loss to Wigan just days later.
Mick McCarthy will be keen to capitalise on this and pull off a win that would help take the heat out of accusations that his Wolves side have too much bite. They have picked up 13 bookings and one red card in their last two matches, and Karl Henry's challenge on Bobby Zamora last week resulted in a broken leg for the Fulham striker.
McCarthy says his side have become the "devil incarnate" in the eyes of the media and fans of other clubs - Fulham supporters chanted "you're a disgrace to the Premiership" at them last weekend - but he maintains his side are completely fair.
There is no doubting, though, that Spurs are a side that struggle against physical teams that like to play a stifling 4-5-1 formation. Wolves used this to great effect last season when they beat Spurs home and away - expect no apologies from McCarthy if they have to flex their muscles to do it again.