Blackburn are without Roque Santa Cruz after he tweaked his groin in the FA Cup defeat by Aston Villa.
Ryan Nelsen and Gael Givet will have late fitness tests, while transfer deadline day signings Mauro Formica and Ruben Rochina will not feature.
Tottenham have a defensive crisis as Michael Dawson is suspended, William Gallas is doubtful and Younes Kaboul sidelined following knee surgery.
Jonathan Woodgate could return after 14 months out with a groin injury.
Both clubs bowed out of the FA Cup at the weekend without so much as a whimper and will now turn their attentions to league campaigns that have a lot at stake.
Having started November just outside the relegation zone, Blackburn have rocketed up the table thanks to an erratic run of results that has seen them alternate between victory and defeat.
They now sit eighth, just two places behind Spurs, and new manager Steve Kean has calmly ridden out the storm caused by Sam Allardyce's departure. Although a marquee signing like David Beckham or Ronaldinho has eluded the club's new owners, they must be very pleased by the top-half position Kean has achieved with a squad that were said to be mutinous only weeks ago.
Tottenham's dreams of winning a trophy at Wembley when the year ends in one took a savage blow when they were thrashed by Fulham, meaning their hopes of glory at the famous stadium now rest on reaching the Champions League final in London in May.
Their prospects of qualifying for the tournament again next season have faltered following a run of three league matches without a win. But the fixture computer has been kind and, with none of the top four to face until the middle of April, Harry Redknapp's side will fancy their chances of leapfrogging Chelsea into fourth and dining at the top table of European football for another year.