Tottenham defender Younes Kaboul begins a three-match suspension as a result of his red card for clashing heads with Newcastle's Cheik Tiote.
William Gallas makes a timely return from a hamstring strain, but Robbie Keane is a doubt with a similar injury.
Fulham goalkeeper Mark Schwarzer will play his last game before flying out to the Asian Cup to represent Australia.
Forward Mousa Dembele is nearing a return after a seven-week absence with an ankle injury.
Having won with 10 men for the second successive match following Younes Kaboul's red card for butting a Newcastle opponent, Tottenham now have a head-to-head in their favour.
They have only lost once in 63 years at home to Fulham and ended the west London side's unbeaten start in the league in October.
Tottenham's recent form has fuelled talk of a title challenge, and anything must feel possible at White Hart Lane these days. Conversely, Fulham begin the year in the bottom three and there were question marks over the future of manager Mark Hughes following the home defeat by West Ham on Boxing Day.
Fulham's subsequent victory at Stoke - their first away win since the opening day of last season - was as deserved as it was unexpected, with Chris Baird scoring his first goals since March 2007. Hughes described the performance as immense; for once, Fulham looked good in khaki.
They displayed a resilience in that game that has been a trademark of Tottenham's performances over the festive period. With their mix of perspiration and inspiration, it is little wonder that Spurs' title odds have shrunk to 20-1.
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